Re-opening & redesigning of the Ocrelizumab (Ocrevus ®) infusion service following the first wave of the COVID-19 Pandemic
Advanced MasterClass 9, November 2020
To review the impact of the COVID-19 pandemic on King’s College Hospital’s ocrelizumab infusion service with a view to restarting and developing it.
- Before the pandemic, the ocrelizumab service at King’s was running three times a week, with a capacity for 12 patients
- When the service was suspended, on 20 March 2020, the average wait time for therapy was 12 to 16 weeks
- By June 2020, 206 patients (64 new and 142 previously treated) were awaiting therapy
- Among the 142 previously treated patients, the delay varied from three weeks to five months
To reinstate the service, the team:
- Flagged the urgent need to service managers
- Worked to make the supplied space suitable for the service – this included working with other departments to secure equipment and deep cleaning or de-cluttering
- Produced a standard operating procedure
- Adopted strict infection control and isolation procedures
- Implemented an MDT-managed traffic light system to prioritise patients in order of clinical need
- Implemented urgent MS nurse clinics to rescreen patients before re-starting treatment
The unit reopened on 13 July 2020. As of 23 October 2020:
- 175 patients (41 new and 143 previously treated) have received treatment at the King’s unit
- 13 have had their care repatriated to local MS services
- 18 decided not to start or continue therapy due to concern over COVID-19 risk
There is currently no waiting list.
The review demonstrated the need for a complete redesign of the ocrelizumab infusion service in the light of the COVID-19 pandemic.
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